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Gloria Yiu, M.D., Ph.D., delves into the transformative potential of genetic editing technologies in addressing rare immune disorders, with a focus on CD3δ severe combined immunodeficiency (SCID)—a condition characterized by impaired T-cell development and severely compromised immune function. Leveraging her expertise as a physician-scientist, Yiu explores how CRISPR and other precision gene-editing tools can correct genetic mutations at the cellular level, potentially restoring T-cell production and immune resilience in patients with CD3δ SCID. Her presentation underscores the challenges and breakthroughs in treating such life-threatening conditions, emphasizing the role of interdisciplinary research, clinical innovation, and ethical considerations in advancing the frontiers of personalized medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40245]
Previous episodes
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1244 - Restoration of T Cell Development in CD3δ SCID Through Adenine Base-Editing with Gloria Yiu - Sanford Stem Cell Symposium 2024Mon, 2 Dec 2024
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1243 - CARTA: Göbekli Tepe with Ricarda BraunSun, 1 Dec 2024
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1242 - Infectious Disease Breakthroughs - Medicine Informing Novel Discoveries (MIND)Sat, 30 Nov 2024
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1241 - What Makes a Stem Cell a Stem Cell and How Does it Go Bad? with John Dick - Sanford Stem Cell Symposium 2024Mon, 25 Nov 2024
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1240 - CARTA: Deep Time Evolution of the Indigenous Peoples and Architectures of Australia with Paul MemmottWed, 20 Nov 2024
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1239 - CARTA: How People Learned to Live in Cities with Michael SmithSat, 16 Nov 2024
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1238 - The Deadly Trade in Oil and GasFri, 15 Nov 2024
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1237 - CARTA: Evolving the Construction-Ready Brain with Michael ArbibMon, 11 Nov 2024
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1236 - Explorations of Telomere Biology in the Context of Human Aging with Elizabeth Blackburn - Sanford Stem Cell Symposium 2024Fri, 8 Nov 2024
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1235 - CARTA: Combinatorial Technology and the Emergence of the Built Environment with Larry BarhamWed, 6 Nov 2024
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1234 - Found in Translation: Development of a Cellular Therapy for Age-Related Macular DegenerationMon, 4 Nov 2024
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1233 - CARTA: Bird Nests: Adaptive Variation on Innate Bauplans with Susan HealyTue, 29 Oct 2024
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1232 - CARTA: How Humans Came to Construct Their Worlds - Welcome and Opening RemarksTue, 29 Oct 2024
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1231 - From Ground To Space: Studying Wicking Aboard The International Space StationSun, 27 Oct 2024
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1230 - CARTA: Energy in the Balance with Barnabas CalderFri, 25 Oct 2024
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1229 - Al for Security Security for AlMon, 21 Oct 2024
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1228 - CARTA: From Cave to Architecture: Settling Down in Southwest Asia with Trevor WatkinsSun, 20 Oct 2024
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1227 - The Link Between Proteins Alzheimer’s and Parkinson’s DiseasesFri, 18 Oct 2024
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1226 - Stem Cells and the Human Brain - Medicine Informing Novel Discoveries (MIND)Wed, 16 Oct 2024
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1225 - CARTA: Lucy - Questions Answers and Closing RemarksSun, 13 Oct 2024
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1224 - CARTA: Naming Lucy: Taxonomic Reasoning in Paleoanthropology with Andra MeneganzinFri, 11 Oct 2024
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1223 - The Problem with Flood Insurance: Can Community Insurance Help?Mon, 7 Oct 2024
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1222 - Black Holes Spacetime and YouWed, 9 Oct 2024
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1221 - CARTA: Fifty Years Since Lucy’s Discovery: Advances in Scientific Knowledge on Human Origins and the Development of African Paleosciences with Yohannes Haile-SelassieFri, 4 Oct 2024
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1220 - Will Dam Removal Save Salmon on the Klamath River?Mon, 30 Sep 2024
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1219 - CARTA: The First Paleo-Rock Star: Is Lucy Still an Influencer? with Ann GibbonsFri, 27 Sep 2024
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1218 - Bioengineering a Kidney Chip for Better Safer and Faster Drug DevelopmentWed, 25 Sep 2024
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1217 - Can Aging be Reversed? Stem Cells as a Key to LongevityFri, 20 Sep 2024
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1216 - California Communities Fighting Climate ChangeWed, 18 Sep 2024
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1215 - CARTA: Lucy African Heritage and ‘Paleodoms’ with Job KibiiFri, 13 Sep 2024
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1214 - Spinal Cord Injury and Plasticity: Breathing After InjuryWed, 11 Sep 2024
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1213 - CARTA: Lucy’s Contribution: Understanding the Sequence of Steps Leading to Human Uniqueness with Kim HillThu, 5 Sep 2024
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1212 - Food Poisoning: Seafood and BacteriaMon, 2 Sep 2024
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1211 - CARTA: Lucy's Legacy and the Past and Future of Primate Research with Melissa Emery ThompsonSat, 31 Aug 2024
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1210 - Upgrading the Physiological Relevance of Human Brain OrganoidsTue, 27 Aug 2024
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1209 - CARTA: How Did Lucy Become a Fossil? Investigating the Life Death and Preservation of a Famous Hominin with Anna BehrensmeyerFri, 23 Aug 2024
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1208 - CARTA: How the Paleo Diet Worked for Lucy-and Led to Us with Jessica ThompsonFri, 16 Aug 2024
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1207 - A Deep Look into Innovation and Equity in the AI RevolutionSun, 18 Aug 2024
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1206 - CARTA: Lucy and Evolution of Hand Dexterity and Tool Use with Tracy KivellSat, 10 Aug 2024
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1205 - CARTA: Lucy - Welcome and Opening RemarksSat, 10 Aug 2024
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1204 - Modeling Kidney Disease and Regeneration with Organoids Derived from Human Pluripotent Stem CellsMon, 5 Aug 2024
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1203 - CARTA: What Was Lucy’s Impact on our Understanding of Bipedality Diet and Encephalization? with Carol WardThu, 1 Aug 2024
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1202 - Our Common Climate: Variability and Climate Change in the U.S. - Mexico Western Border RegionWed, 31 Jul 2024
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1201 - CARTA: The Savanna Hypothesis: Tracing an Enigmatic Idea Through Time with Kaye ReedFri, 26 Jul 2024
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1200 - CARTA: What Was Lucy’s Impact on Our Understanding of Other Australopith Relatives? with Bernard WoodMon, 22 Jul 2024
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1199 - CARTA: Lucy's Children and Human Origins with Zeray AlemsegedThu, 18 Jul 2024
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1198 - CARTA: The Discovery and Initial Interpretation of ‘Lucy’ as a Tipping-Point in Paleoanthropology with Ian TattersallSat, 13 Jul 2024
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1197 - A Closer Look at...Stem Cells and Human LongevityThu, 11 Jul 2024
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1196 - Capturing Late-Onset Neurodegeneration in Patient-Derived Neurons via Direct Reprogramming - Breaking News in Stem CellsTue, 9 Jul 2024
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1195 - Building Fast and Reliable Machine Learning Systems with Yian MaWed, 3 Jul 2024
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